Crystal structure of (+)-(4S,5R,2’R,4’S,5’R,1’’S)-5-(2’’-acetoxy-1’’- benzyloxy-ethyl)-3-(5’-acetoxy-2’-methyl-1’,3’-dioxan-4’-yl)-4-(tert-butoxycarbonylamino)-4,5-dihydro-isoxazole, C26H36N2O10

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Synthesis and Leishmanicidal Activity of 1-[5-(5-nitrofuran-2-yl)-1, 3, 4-thiadiazole-2-yl]-4-benzoylepiperazines

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Synthesis and Leishmanicidal Activity of 1-[5-(5-nitrofuran-2-yl)-1, 3, 4-thiadiazole-2-yl]-4-benzoylepiperazines

A series of (5-nitrofuran-2-yl)-1, 3, 4-thiadiazole-2-yl derivatives 6a–6e have been synthesized and screened for in vitro anti-leishmanial activity against the promastigote form of L. major. The structure of Schiff bases were confirmed by 1H NMR, IR. Screening results indicate that all of the designed and synthesized final compounds (6a-6e) significantly reduced the viability of promastigotes ...

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ژورنال

عنوان ژورنال: Zeitschrift für Kristallographie - New Crystal Structures

سال: 2000

ISSN: 2197-4578,1433-7266

DOI: 10.1515/ncrs-2000-0168